Anatomic Basis of Tumor Surgery 2nd Ed

Detalles del producto

Hardcover: 866 páginas
Editor: Springer; Edición: 2nd ed. 2010 (23 de diciembre de 2009)
Idioma: English
ISBN-10: 3540741763
ISBN-13: 978-3540741763
Dimensiones del producto: 22.2 x 4.4 x 27.9 cm
Peso del envío: 7.1 pounds

Modern biological understanding is the basis for a multimodality treatment of a tumor. ‘Anatomic Basis of Tumor Surgery’ is the only book that provides an anatomic basis and description of tumor surgery based on an understanding of both the anatomy and biology of tumor progression. It presents the regional anatomy to allow tailoring of the operation as demanded.

The old saying that “the best anatomist makes the best surgeon” is but a variation on the venerable saw that “you have to know the territory.” Neoplastic disease has no respect for anatomical boundaries, making detailed familiarity with anatomy that exists beyond the margins of a standard surgical method a great facilitator for many surgical procedures. The biology of cancer and knowledge of all modalities appropriate for its management continues to defi ne new approaches to both common and rare cancers.

We are pleased to present this update of Anatomic Basis of Tumor Surgery, the 2nd edition of the book that interweaves the form of an atlas, the shape of an anatomy text, and a pervasive understanding of multimodality therapy in light of the expanding knowledge of oncologic biology. In addition to welcoming many new authors to this edition, Charles Staley has joined us as an editor. We also honor John Skandalakis for holding aloft the torch of surgical anatomy with so many contributions over the nearly ninety years of his life.

Many thanks are owed to Sean Moore, Editor for the Department of Surgery at Emory, whose diligent reviews and persistent eff orts brought this book to completion.

Charles A. Staley
William C. Wood
John E. Skandalakis †
Atlanta, Georgia, USA

Malignant tumors of the oral cavity and oropharynx are predominantly (greater than 90–95%) squamous cell carcinomas. Less common tumors include minor salivary gland tumors (especially on the hard palate), verrucous carcinomas, lymphomas, melanomas, and sarcomas. The most common risk factors are tobacco, smoked and smokeless, and alcohol abuse. Less common factors include poorly fi tting dentures, poor dentition with irregular surfaces, and poor oral hygiene. Nonsmokers can also be diagnosed with oral cavity and oropharynx cancer. Among nonsmokers, human papillomavirus (HPV) has recently been associated with malignancies of the oropharynx, and may portend better outcomes when compared to those without HPV infection. Malignancies of the oral cavity and oropharynx account for approximately 4% of all newly diagnosed nonskin malignancies, with a 2:1 male predominance.

Approximately 34,000 new cases are diagnosed each year. Two-thirds of these are in the oral cavity and one-third in the oropharynx. Oral cancer accounts for an estimated 7,550 deaths yearly (Cancer Facts and Figures, 2007). While oral cavity and oropharynx cancer accounts for only a small number of all new cancers, the functional problems created by these tumors and their treatment are signifi cant. Oral cavity and pharyngeal dysfunction affects speech, oral competence, the fi rst and second (oral and pharyngeal) phases of swallowing, and in some instances, the ability to adequately protect the airway. Even small tumors may result in signifi cant weight loss due to pain, dysphagia, and odynophagia, resulting in malnutrition. Dysarthria affects interpersonal communication and frequently results in withdrawal from public situations.

An important consideration in the treatment of oral cavity and oropharyngeal malignancies is the high incidence of second primary tumors. These tumors may be synchronous or metachronous, and occur in approximately 20% of patients. More than half of these second primary tumors are found in the upper airway and digestive tract, most commonly in the esophagus, larynx, oral cavity, and pharynx, as a result of the widespread carcinogenic effects of tobacco and alcohol. Second primary cancers of the lung are also common and for the same reasons. Pretreatment evaluation with chest radiography or computed tomography (CT), positron emission testing (PET), and rigid laryngoscopy and esophagoscopy, is advised to fully stage these tumors.