Infomedik
Menu
  • Home
  • E-Books
      • Médicos
        • libros-medicos@2xLibros Médicos
        • journals01Medical Journals
        • revistas-medicos@2xRevistas de Salud
        • tutmedTutoriales Médicos
      • Pacientes
        • libros-pacientes@2xLibros para Pacientes
        • revistas-pacientes@2xRevistas para Pacientes
      • Estilo de Vida
      • Libros en General
  • Imágenes
      • Fotos Stock
        • hospitalHospitales
        • medicosMédicos
        • anatomyAnatomía
        • saludSalud
        • dentalDental
      • Graphic Stock
        • aminacionesAnimaciones
        • vectoresVectores
        • iconsÍconos
        • wallpaperFondos
        • infografiaInfografías
  • Plantillas
      • Redes Sociales
        • Facebook03Facebook
        • Instagram03Instagram
        • Twitter04Twitter
        • youtube05YouTube
  • Papelería
      • Diseño Papelería Médica
        • revistasRevistas
        • brochureTrípticos
        • dipticosDípticos
        • diplomaDiplomas
        • curriculumCurriculum
        • businessBusiness Plan
        • posterPosters
        • bannersBanners
        • landingLanding Page
  • Apps
      • Programas y Aplicaciones
        • iosiOS Apple
        • androidAndroid
        • windowsWindows
        • macMac
  • Música
      • Por décadas
        • 60s60’s
        • 70s70’s
        • 80s80’s
        • 90s90’s
        • 2000s2000
        • 2010s2010
        • 2020s2020
      • Por Género
        • classic-musicClassic Music
        • operaOpera
        • jazzJazz
        • rockRock
        • countryCountry
        • discoDisco
        • r&bRythm & Blues
        • rapRap
        • popPop
        • raggaeReggae
        • hiphopHipHop
        • electronicElectronic
        • houseHouse Music
        • mexicanMexican Music
  • Diseño Web
      • Diseño Internet
        • webdesignDiseño Páginas Internet
        • instagramdesignDiseño Instagram
        • facebookdesignDiseño Facebook
        • socialmediaMarketing Redes Sociales
      • Audio y Video
        • medicalyoutubeMedical YouTube Channel
        • entrevistatvEntrevistas TV
        • entrevistaradioEntrevistas Radio
        • videoxrdVideos Personalizados
      • Presentaciones Médicas
        • powerpointPowerPoint
        • KeynoteKeynote
Menu
Infomedik
0 items / $0.00
InicioE-BooksE-Books Médicos Autophagy, Infection and the Immune Response
Previous product
Autoimmune Diseases of the Skin
Back to products
Next product
Biology of Disease

Autophagy, Infection and the Immune Response

Product details

  • File Size: 10126 KB
  • Print Length: 327 pages
  • Page Numbers Source ISBN: 1118677641
  • Publisher: Wiley-Blackwell; 1 edition (December 3, 2014)
  • Publication Date: December 3, 2014
  • Sold by: Amazon.com Services LLC
  • Language: English
  • ASIN: B00QM8O5BO
  • Text-to-Speech: Enabled
  • X-Ray: Not Enabled
  • Word Wise: Not Enabled
  • Lending: Not Enabled
  • Enhanced Typesetting: Not Enabled

 

Since the discovery nearly 20 years ago that pathogenic bacteria and viruses intimately associate with autophagosomal membranes, scientists have determined that autophagy is a critical component of innate and acquired immunity. Of course, as with all aspects of the host immune response, some pathogens have turned autophagy to their advantage.

For this volume, experts in the fields of bacteriology, virology, mycology, parasitology, immunology, and cell biology describe the cellular mechanisms of autophagosome formation and maturation, its contribution to host defenses, and the mechanisms pathogenic microbes have acquired to overcome and subvert this formidable barrier to infection.

In addition, specialists discuss current efforts to exploit knowledge of the autophagy pathway to improve vaccine design. Accordingly, this thorough examination of an extraordinary cellular battleground between host and pathogen can stimulate ongoing research to understand and to manipulate autophagy to improve human health.

Categoría: E-Books Médicos Etiquetas: Alergia e Inmunología, Infectología
  • Descripción
  • Por qué utilizar archivos PDF
Descripción

Autophagy is a highly controlled process in which cellular components are self-degraded and subsequently recycled. This pathway in part plays a “house cleaning” role in the cell, directing numerous cargoes to the lysosome (or the vacuole in yeast and plants) for degradation. Depending on the specific conditions, the cargoes include random portions of cytoplasm, protein aggregates, and damaged or superfluous organelles such as mitochondria and peroxisomes. Dysfunction of autophagy is linked with many pathologies, including cancer, diabetes, myopathies, heart, liver and lung diseases, and certain types of neurodegenerative disease (Castets et al., 2013; Gonzalez et al., 2011; Klionsky and Codogno, 2013; Murrow and Debnath, 2013; Rubinsztein et al., 2012; Yang and Klionsky, 2010).

Emerging studies have revealed that autophagy plays important roles in immunity. In 2004, independent studies demonstrated for the first time that invading pathogens can be cargoes for autophagy (Gutierrez et al., 2004; Nakagawa et al., 2004). Today it is well accepted that autophagy can directly eliminate intracellular pathogens, including bacteria, fungal parasites, and viruses. Autophagy can also activate innate immune signaling cascades such as Toll-like receptor (TLR) signaling to attack invading pathogens (Lee et al., 2007; Xu et al., 2007). However, microbes constantly undergo strong selective pressure to develop strategies to block host defense mechanisms autophagy through distinct mechanisms (Deretic and Levine, 2009; Kuballa et al., 2012; Levine et al., 2011; Yuk et al., 2012; Zhou and Zhang, 2012).

Autophagy’s role in immunity is not limited to controlling infection by direct elimination of pathogens. For example, autophagy facilitates MHC (major histocompatibility complex) antigen presentation, indicating that autophagy is involved in adaptive as well as innate immunity (English et al., 2009; Paludan et al., 2005). Moreover, defects in autophagy are associated with autoimmune diseases such as Crohn disease (Levine et al., 2011; Schroder and Tschopp, 2010; Shi et al., 2012). Thus, autophagy is an integral part of our response to infection and plays a key role in immunity. A comprehensive understanding of autophagy as it pertains to microbial infection and the molecular mechanisms that underlie the interplay between autophagy and immune signaling pathways may enable us to unravel the pathogenesis of many infectious and immune diseases, and develop more effective therapeutic strategies for their treatment.

Por qué utilizar archivos PDF

Productos relacionados

Quick view
Leer más
Close

Users’ Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice, Third Edition

Quick view
Leer más
Close

Allergy – An Atlas of Investigation and Management

Quick view
Leer más
Close

Auto-Immunity Attacks the Body – Autoimmune Disease 2017

Quick view
Leer más
Close

Immunology: A Short Course

Quick view
Leer más
Close

Principles of Medical Statistics

Quick view
Leer más
Close

Immunogenomics And Human Disease

Quick view
Leer más
Close

History of Medical Bacteriology and Immunology

Quick view
Leer más
Close

Handbook of Human Immunology

Quick view
Leer más
Close

Avoiding Medical Errors: One Hundred Rules to Help You Survive Mistakes by Doctors and Hospitals

Quick view
Leer más
Close

Common Malformations

Quick view
Leer más
Close

Immunology: Mucosal and Body Surface Defences

Quick view
Leer más
Close

Cutaneous Manifestations of Infection in the Immunocompromised Host

Vitra
Magisso
Louis Poulsen
KLÖBER
Joseph Joseph
Hay
Flos
Eva Solo
Alessi

Toda la Información Médica necesaria para apoyar su práctica médica, desde una revista hasta un programa de televisión.

Río Tigris # 86,
Colonia Cuauhtémoc,
06600, México
info@ccmedia.org
CCEMEdia, AC
Recent Posts
Our Stores
  • New York
  • London SF
  • Cockfosters BP
  • Los Angeles
  • Chicago
  • Las Vegas
Useful links
  • Privacy Policy
  • Returns
  • Terms & Conditions
  • Contact Us
  • Latest News
  • Our Sitemap
Footer Menu
  • Instagram profile
  • New Collection
  • Woman Dress
  • Contact Us
  • Latest News
  • Purchase Theme
Infomedik 1998 - 2020 Todos los Derechos Reservados - CCEMedia AC
close
Start typing to see products you are looking for.
Menu
  • Blog

Shopping cart

close
Scroll To Top

HEY YOU, SIGN UP AND CONNECT TO WOODMART!

Be the first to learn about our latest trends and get exclusive offers

Will be used in accordance with our Privacy Policy

We use cookies to improve your experience on our website. By browsing this website, you agree to our use of cookies. Utilizamos cookies para mejorar su experiencia en nuestro sitio de Internet. Si navega a través de este sitio usted acepta el uso de cookies.
Accept