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InicioE-BooksE-Books Médicos Immunology: A Short Course
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Immunology: Mucosal and Body Surface Defences

Immunology: A Short Course

Product details

  • File Size: 9.62 Gb
  • Print Length: 433 pages
  • Year: 2015
  • Publisher: Wiley-Blackwell; 7 edition (January 28, 2015)
  • Publication Date: January 28, 2015
  • Sold by: Amazon.com Services LLC
  • Language: English
  • ISBN: 978-1-118-39691-9
  • Text-to-Speech: Enabled
  • X-Ray: Not Enabled
  • Word Wise: Not Enabled
  • Lending: Not Enabled
  • Screen Reader: Supported
  • Enhanced Typesetting: Enabled

 

Immunology: A Short Course, 7th Edition introduces all the critical topics of modern immunology in a clear and succinct yet comprehensive fashion. The authors offer uniquely-balanced coverage of classical and contemporary approaches and basic and clinical aspects. The strength of Immunology: A Short Course is in providing a complete review of modern immunology without the burden of excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics, illustrated by uniformly drawn, full-color illustrations and photographs.

This new edition of Immunology: A Short Course:

• Has been fully revised and updated, with a brand new art program to help reinforce learning
• Includes a new chapter on Innate Immunity to reflect the growth in knowledge in this area
• Highlights important therapeutic successes resulting from targeted antibody therapies
• Includes end of chapter summaries and review questions, a companion website at www.wileyimmunology.com/coico featuring interactive flashcards, USMLE-style interactive MCQs, figures as PowerPoint slides, and case-based material to help understand clinical applications

Categoría: E-Books Médicos Etiquetas: Alergia e Inmunología, Genética
  • Descripción
  • Por qué utilizar archivos PDF
Descripción

Anyone who has had the good fortune to hear an orchestra brilliantly perform a symphony composed by one of the great masters knows that each of the carefully tuned musical instruments contributes to the collective, harmonious sound produced by the musicians. In many ways, the normally tuned immune system continuously plays an orchestrated symphony to maintain homeostasis in the context of host defenses. However, as William Shakespeare noted, “Untune that string, and, hark, what discord follows!” (Troilus and Cressida). Similarly, an untuned immune system can cause discord, which manifests as autoimmunity, cancer, or chronic inflammation. Fortunately for most of us, our immune system is steadfastly vigilant in regard to tuning (regulating) itself to ensure that its cellular components behave and interact symbiotically to generate protective immune responses that ensure good health. In many ways the immune system can be described in anthropomorphic terms: Its memory allows it to remember and recognize pathogens years or decades after initial exposure; it can distinguish between the body’s own cells and those of another organism; and it makes decisions about how to respond to particular pathogens—including whether or not to respond at all, as will be discussed in Chapters 2 and 3.

In his penetrating essays, scientist–author Lewis Thomas, discussing symbiosis and parasitism, described the forces that would drive all living matter into one huge ball of protoplasm were it not for regulatory and recognition mechanisms that allow us to distinguish self from nonself.

The origins of these mechanisms go far back in evolutionary history, and many, in fact, originated as markers for allowing cells to recognize and interact with each other to set up symbiotic households. Genetically related sponge colonies that are placed close to each other, for example, will tend to grow toward each other and fuse into one large colony. Unrelated colonies, however, will react in a different way, destroying cells that come in contact with each other and leaving a zone of rejection between the colonies. In the plant kingdom, similar types of recognition occur. In self-pollinating species, a pollen grain landing on the stigma of a genetically related flower will send a pollen tubule down the style to the ovary for fertilization. A pollen grain from a genetically distinct plant either will not germinate or the pollen tubule, once formed, will disintegrate in the style. The opposite occurs in cross-pollinating species: self-marked pollen grains disintegrate, whereas nonself grains germinate and fertilize.

Por qué utilizar archivos PDF

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