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InicioE-BooksE-Books Médicos Immunology: Mucosal and Body Surface Defences
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Immunology: Mucosal and Body Surface Defences

Product details

  • File Size: 46164 KB
  • Print Length: 398 pages
  • Publisher: Wiley; 1 edition (October 5, 2011)
  • Publication Date: October 5, 2011
  • Sold by: Amazon.com Services LLC
  • Language: English
  • ASIN: B006DEDKGI
  • Text-to-Speech: Enabled
  • X-Ray: Not Enabled
  • Word Wise: Not Enabled
  • Lending: Not Enabled
  • Enhanced Typesetting: Enabled

 

The vast majority of medically important pathogens infect their host across a body surface such as the skin, or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. By focusing on immunity at mucosal and body surfaces this book presents a fresh, new approach to the teaching of immunology.

After an introduction to the basic structure of the immune system, the book looks at two important families of signalling molecules: cytokines and chemokines, before covering the workings of the mucosal immune system. It continues by examining immunity against the four major groups of pathogens – viruses, bacteria, fungi and parasites, and concludes by looking at disorders of the immune system, mucosal tumour immunology and the process of vaccination.

  • A fresh, new approach to the subject focusing on mucosal and body surfaces.
  • Describes the mucosal immune systems of the gastrointestinal, respiratory and urogenital tracts, as well as the skin.
  • Details the important roles of cytokines and chemokines in an immune response.
  • Separate chapters devoted to immunity against viruses, bacteria, fungi and parasites.
  • Includes chapter summaries, boxes with topics of special interest and an extensive glossary.
  • Clearly written and well- illustrated in full colour throughout.

Students across a range of disciplines, including biology, biochemistry, biomedicine, medicine and veterinary sciences, will find this book invaluable, both as an introduction to basic immunology and as a guide to mucosal immune defence mechanisms.

Categoría: E-Books Médicos
  • Descripción
  • Por qué utilizar archivos PDF
Descripción

For thousands of years humans have marvelled at how the body is able to protect itself from infectious pathogens. Even the ancient Chinese and Greeks acknowledged the protective effects of the immune system, noting how one is rendered resistant to catching the same disease a second time. The first empirical studies were performed by Edward Jenner, and later Louis Pasteur, who developed vaccines against smallpox and anthrax, respectively. Indeed, vaccination has become such an important aspect of human health it is sometimes easy to forget the central role the immune system plays in affording protection against so many diseases.

The vast majority of medically important pathogens infect their host across a body surface such as the skin, or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. Vertebrates have therefore evolved elaborate immune defence mechanisms to protect against infection across mucosal linings and body surfaces. Mucosal immune defence mechanisms are therefore integral to our survival. However, conventional immunology textbooks largely overlook this aspect of the immune system, even though it remains fundamental for the prevention of infectious disease. Many have continued to teach immunology based on knowledge of the central immune system of the blood and spleen, rather than teaching immunology from the perspective of mucosal and body surfaces. After all, these are the places where host–pathogen interactions actually take place. Therefore I have tried to redress this bias by focusing on immunity at mucosal and body surfaces. This book should therefore prove useful for science undergraduates studying immunology, medical students undertaking academic studies, postgraduate students working toward a higher degree and the broad spectrum of professional academic and clinical scientists working in the field of immunology.

Por qué utilizar archivos PDF

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